Marijuana Medicine

Floxed mouse line of cannabinoid receptor 2 (CB2R) gene conditional knockout as an animal model for medicinal marijuana development.

The present invention relates to a genetically modified mouse wherein the mouse is able to produce a model of deletion of the Cnr2 gene in certain cell types. These cell types include dopaminergic, glutamatergic, GABAergic, cholinergic, astrocyte, oligodendrocyte, microglia and immune cell specific deletion of Cnr2 gene.

Patent: Onaivi ES, Liu QR. , inventors. WILLIAM PATERSON UNIVERSITY, assignee.
United States US 62/121227. 2015 March 13.

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